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Lidocaine Hydrochloride Injection

Brand names: Lidocaine, Lidocaine Hydrochloride, Lidocaine Hydrochloride And Dextrose, Xylocaine, Xylocaine Mpf

Category: Analgesia/Addiction, Anesthesia, Cardiovascular, Pediatric

Unavailable 21Limited 1Available 43Not specified 2

FDA status: Current, To Be Discontinued · Last FDA update: Nov 7, 2025 · First posted: Feb 20, 2018 (in shortage 8 years 7 months) · 10 manufacturers, 67 listed presentations

As of Nov 7, 2025, the FDA lists Lidocaine Hydrochloride Injection as being discontinued. Of 67 manufacturer presentations, 21 Unavailable, 1 Limited, 43 Available, 2 Not specified.

Ask your pharmacist: which of the 10 manufacturers below can they order right now, and whether a different strength or form of Lidocaine Hydrochloride Injection is available. For alternatives, talk to your prescriber — see what to do if your medication is in shortage.
Presentation & package NDCManufacturerAvailabilityFDA note
Lidocaine Hydrochloride And Dextrose, Injection, 4 mg/1 mL (NDC 0338-0409-03)
NDC 0338-0409-03
Baxter Healthcare Available -
Lidocaine Hydrochloride And Dextrose, Injection, 5 g/100 mL; .4 g/100 mL (NDC 0264-9594-10)
NDC 0264-9594-10
B. Braun Medical Inc. Available -
Lidocaine Hydrochloride And Dextrose, Injection, 5 g/100 mL; .4 g/100 mL (NDC 0264-9594-20)
NDC 0264-9594-20
B. Braun Medical Inc. Available -
Lidocaine Hydrochloride And Dextrose, Injection, 5 g/100 mL; .8 g/100 mL (NDC 0264-9598-20)
NDC 0264-9598-20
B. Braun Medical Inc. Available -
Xylocaine, Injection, 5 mg/1 mL (NDC 63323-484-57)
NDC 63323-484-57
Fresenius Kabi USA, LLC Unavailable Estimated recovery: TBD
Xylocaine, Injection, 5 mg/1 mL (NDC 63323-491-57)
NDC 63323-491-57
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Lidocaine Hydrochloride And Dextrose, Injection, 8 mg/1 mL (NDC 0338-0411-02)
NDC 0338-0411-02
Baxter Healthcare Available -
Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-159-74)
NDC 55150-159-74
Eugia US LLC Unavailable On backorder. Recovery: TBD. Check wholesalers for inventory
Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-161-02)
NDC 55150-161-02
Eugia US LLC Unavailable On backorder. Recovery: late October 2026. Check wholesalers for inventory
Xylocaine, Injection, 10 mg/1 mL (NDC 63323-492-31)
NDC 63323-492-31
Fresenius Kabi USA, LLC Unavailable Estimated recovery: TBD
Xylocaine, Injection, 10 mg/1 mL (NDC 63323-492-27)
NDC 63323-492-27
Fresenius Kabi USA, LLC Unavailable Next release October 2026. Check wholesalers for inventory.
Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 63323-201-10)
NDC 63323-201-10
Fresenius Kabi USA, LLC Unavailable Next release October 2026. Check wholesalers for inventory.
Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 73293-0001-2)
NDC 73293-0001-2
Huons Co., Ltd. (South Korea) Unavailable Estimated recovery: TBD
Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 65282-1605-1)
NDC 65282-1605-1
Spectra Medical Devices, LLC Unavailable Estimated recovery: TBD
Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-163-30)
NDC 55150-163-30
Eugia US LLC Available Check wholesalers for inventory
Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-162-05)
NDC 55150-162-05
Eugia US LLC Available Check wholesalers for inventory
Xylocaine, Injection, 10 mg/1 mL (NDC 63323-485-27)
NDC 63323-485-27
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Xylocaine, Injection, 10 mg/1 mL (NDC 63323-485-57)
NDC 63323-485-57
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Xylocaine, Injection, 10 mg/1 mL (NDC 63323-492-57)
NDC 63323-492-57
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Xylocaine, Injection, 10 mg/1 mL (NDC 63323-492-37)
NDC 63323-492-37
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Lidocaine Hydrochloride In Plastic Container, Injection, 10 mg/1 mL (NDC 63323-201-02)
NDC 63323-201-02
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Lidocaine Hydrochloride, Preservative Free, Injection, 10 mg/1 mL (NDC 0143-9595-25)
NDC 0143-9595-25
Hikma Pharmaceuticals USA, Inc. Available Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 0143-9577-10)
NDC 0143-9577-10
Hikma Pharmaceuticals USA, Inc. Available Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Lidocaine Hydrochloride Preservative Free In Plastic Container, Injection, 50 mg/5mL (1%, 10 mg/1 mL) Syringes (NDC 0409-9137-05)
NDC 0409-9137-05
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride, Injection, 10 mg/mL (NDC 55150-252-20)
NDC 55150-252-20
Eugia US LLC Unavailable On backorder. Recovery: late September 2026. Check wholesalers for inventory
Lidocaine Hydrochloride, Injection, 10 mg/mL (NDC 55150-251-10)
NDC 55150-251-10
Eugia US LLC Unavailable On backorder. Recovery: TBD. Check wholesalers for inventory
Xylocaine, Injection, 15 mg/1 mL (NDC 63323-493-91)
NDC 63323-493-91
Fresenius Kabi USA, LLC Unavailable Estimated recovery: TBD
Xylocaine, Injection, 15 mg/1 mL (NDC 63323-493-97)
NDC 63323-493-97
Fresenius Kabi USA, LLC Unavailable Estimated recovery: TBD
Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 55150-165-05)
NDC 55150-165-05
Eugia US LLC Unavailable On backorder. Recovery: late September 2026. Check wholesalers for inventory
Xylocaine, Injection, 20 mg/1 mL (NDC 63323-496-97)
NDC 63323-496-97
Fresenius Kabi USA, LLC Unavailable Estimated recovery: TBD
Xylocaine, Injection, 20 mg/1 mL (NDC 63323-495-07)
NDC 63323-495-07
Fresenius Kabi USA, LLC Unavailable Next release September 2026. Check wholesalers for inventory.
Xylocaine, Injection, 20 mg/1 mL (NDC 63323-486-27)
NDC 63323-486-27
Fresenius Kabi USA, LLC Unavailable Next release October 2026. Check wholesalers for inventory.
Lidocaine Hydrochloride Preservative Free, Injection, 20 mg/1 mL (NDC 63323-208-05)
NDC 63323-208-05
Fresenius Kabi USA, LLC Unavailable Next release October 2026. Check wholesalers for inventory.
Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 76329-3390-1)
NDC 76329-3390-1
Amphastar Pharmaceuticals, Inc. Limited Available on allocation
Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 63323-202-02)
NDC 63323-202-02
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Xylocaine, Injection, 20 mg/1 mL (NDC 63323-486-57)
NDC 63323-486-57
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Xylocaine, Injection, 20 mg/1 mL (NDC 63323-495-27)
NDC 63323-495-27
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Xylocaine, Injection, 20 mg/1 mL (NDC 63323-486-17)
NDC 63323-486-17
Fresenius Kabi USA, LLC Available Check wholesalers for inventory
Lidocaine Hydrochloride, Preservative Free, Injection, 20 mg/1 mL (NDC 0143-9594-25)
NDC 0143-9594-25
Hikma Pharmaceuticals USA, Inc. Available Additional lots are scheduled to be manufactured. Product will be made available as it is released.
Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 0143-9575-10)
NDC 0143-9575-10
Hikma Pharmaceuticals USA, Inc. Available Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Lidocaine Hydrochloride Preservative Free In Plastic Container, Injection, 100 mg/5mL (2%,20 mg/1 mL) Syringes (NDC 0409-1323-05)
NDC 0409-1323-05
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride, Injection, 20 mg/2 mL (NDC 83634-653-02)
NDC 83634-653-02
Anthea Pharma Available Distributed by Avenacy, LLC
Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-256-50)
NDC 55150-256-50
Eugia US LLC Unavailable On backorder. Recovery: TBD. Check wholesalers for inventory
Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-255-20)
NDC 55150-255-20
Eugia US LLC Unavailable On backorder. Recovery: late September 2026. Check wholesalers for inventory
Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-254-10)
NDC 55150-254-10
Eugia US LLC Unavailable On backorder. Recovery: TBD. Check wholesalers for inventory
Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-164-02)
NDC 55150-164-02
Eugia US LLC Available Check wholesalers for inventory
Lidocaine Hydochloride, Injection, 50 mg/5 mL (NDC 83634-653-05)
NDC 83634-653-05
Anthea Pharma Available Distributed by Avenacy, LLC
Lidocaine Hydrochloride, Injection, 100 mg/10 mL (NDC 83634-651-10)
NDC 83634-651-10
Anthea Pharma Available Distributed by Avenacy, LLC
Lidocaine Hydrochloride, Injection, 200 mg/20 mL (NDC 83634-651-20)
NDC 83634-651-20
Anthea Pharma Available Distributed by Avenacy, LLC
Lidocaine Hydrochloride, Injection, 300 mg/30 mL (NDC 83634-653-30)
NDC 83634-653-30
Anthea Pharma Available Distributed by Avenacy, LLC
Lidocaine Hydrochloride, Injection, 500 mg/50 mL (NDC 83634-651-50)
NDC 83634-651-50
Anthea Pharma Available Distributed by Avenacy, LLC
Lidocaine Hydrochloride In Plastic Container, Injection, 1,000 mg/50 mL (2%; 20 mg/mL) (NDC 0409-4277-02)
NDC 0409-4277-02
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride In Plastic Container, Injection, 200 mg/20 mL (1%; 10 mg/mL) (NDC 0409-4276-01)
NDC 0409-4276-01
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride In Plastic Container, Injection, 250 mg/50 mL (0.5%; 5 mg/mL) (NDC 0409-4275-01)
NDC 0409-4275-01
Hospira, Inc., a Pfizer Company Unavailable Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay
Lidocaine Hydrochloride In Plastic Container, Injection, 400 mg/20 mL (2%; 20 mg/mL) (NDC 0409-4277-01)
NDC 0409-4277-01
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride In Plastic Container, Injection, 500 mg/50 mL (1%; 10 mg/mL) (NDC 0409-4276-02)
NDC 0409-4276-02
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride Preservative Free, Injection, 20 mg/2 mL (1%; 10 mg/mL) (NDC 0409-4713-32)
NDC 0409-4713-32
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride Preservative Free, Injection, 200 mg/5 mL (4%; 40 mg/mL) (NDC 0409-4283-01)
NDC 0409-4283-01
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride Preservative Free, Injection, 300 mg/20 mL (1.5%; 15 mg/mL) (NDC 0409-4776-01)
NDC 0409-4776-01
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride Preservative Free, Injection, 50 mg/5 mL (1%; 10 mg/mL) (NDC 0409-4713-02)
NDC 0409-4713-02
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride, Injection, 1%, USP (For Cardiac Use Only) 50 mg/5 mL (10 mg/mL) LifeShield™ ABBOJECT® Glass Syringe (20 G x 1 1/2) (NDC 0409-4904-34)"
NDC 0409-4904-34
Hospira, Inc., a Pfizer Company Not specified Discontinuation of the manufacture of the drug
Lidocaine Hydrochloride, Injection, 100 mg/5 mL (2%; 20 mg/mL) (NDC 0409-2066-05)
NDC 0409-2066-05
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride, Injection, 2%, USP (For Cardiac Use Only) 100 mg/5 mL (20 mg/mL) LifeShield® ABBOJECT® Glass Syringe (20 G x 1 1/2) (NDC 0409-4903-34)"
NDC 0409-4903-34
Hospira, Inc., a Pfizer Company Not specified Discontinuation of the manufacture of the drug
Lidocaine Hydrochloride, Injection, 200 mg/10 mL (2%; 20 mg/mL) (NDC 0409-4282-02)
NDC 0409-4282-02
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride, Injection, 250 mg/50 mL (0.5%; 5 mg/mL) (NDC 0409-4278-01)
NDC 0409-4278-01
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride, Injection, 300 mg/30 mL (1%; 10 mg/mL) (NDC 0409-4279-02)
NDC 0409-4279-02
Hospira, Inc., a Pfizer Company Available -
Lidocaine Hydrochloride, Injection, 40 mg/2 mL (2%; 20 mg/mL) (NDC 0409-4282-01)
NDC 0409-4282-01
Hospira, Inc., a Pfizer Company Available -

Related medications in shortage

Other Analgesia/Addiction, Anesthesia, Cardiovascular, Pediatric medications currently on the FDA shortage list — useful context if you and your prescriber are weighing alternatives. Always confirm with your pharmacist.

Change log

No changes recorded yet.
Tracking began Oct 1, 2026. We check the FDA every 6 hours; any real change - a manufacturer moving from Limited to Available, a new recovery date, a new listing - shows up here with its date.

Cite this: “FDA drug-shortage status for Lidocaine Hydrochloride Injection (FDA data as of Nov 7, 2025). Shortage Watch, openFDA.”

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FDA data last synced Oct 1, 2026 (FDA record dated Sep 30, 2026).