When will Sodium Bicarbonate Injection be back in stock?

The FDA lists an estimated recovery date per manufacturer where known; check the FDA note column below. National FDA records do not reflect your local pharmacy's shelf.

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Sodium Bicarbonate Injection

Brand names: Sodium Bicarbonate

Category: Endocrinology/Metabolism, Gastroenterology, Pediatric

Unavailable 1Limited 3Available 7Not specified 4

FDA status: Current, To Be Discontinued · Last FDA update: Nov 7, 2025 · First posted: Mar 1, 2017 (in shortage 9 years 7 months) · 5 manufacturers, 15 listed presentations

As of Nov 7, 2025, the FDA lists Sodium Bicarbonate Injection as being discontinued. Of 15 manufacturer presentations, 1 Unavailable, 3 Limited, 7 Available, 4 Not specified.

Ask your pharmacist: which of the 5 manufacturers below can they order right now, and whether a different strength or form of Sodium Bicarbonate Injection is available. For alternatives, talk to your prescriber — see what to do if your medication is in shortage.

Presentation & package NDC	Manufacturer	Availability	FDA note
Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-01) NDC 0409-5555-01	Hospira, Inc., a Pfizer Company	Limited	Limited Supply Available. Next Delivery: May 2027; Estimated Recovery: June 2027; Shortage per Manufacturer: Manufacturing Delay
Sodium Bicarbonate, Injection, 2.5 mEq/5 mL (4.2%, 0.5 mEq/mL) (NDC 0409-5555-02) NDC 0409-5555-02	Hospira, Inc., a Pfizer Company	Limited	Limited Supply Available. Next Delivery: October 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay
Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-35) NDC 0409-6625-35	Hospira, Inc., a Pfizer Company	Unavailable	Next Delivery: January 2027; Estimated Recovery: March 2027; Shortage per Manufacturer: Manufacturing Delay
Sodium Bicarbonate, Injection, 50 mEq/50 mL (8.4%, 1 mEq/mL) (NDC 0409-6625-14) NDC 0409-6625-14	Hospira, Inc., a Pfizer Company	Available	-
Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 51754-5012-4) NDC 51754-5012-4	Exela Pharma Sciences, LLC	Available	-
Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 63323-083-05) NDC 63323-083-05	Fresenius Kabi USA, LLC	Available	Check wholesalers for inventory.
Sodium Bicarbonate, Injection, 42 mg/1 mL (NDC 0409-5534-14) NDC 0409-5534-14	Hospira, Inc., a Pfizer Company	Not specified	Discontinuation of the manufacture of the drug
Sodium Bicarbonate, Injection, 75 mg/1 mL (NDC 0409-4916-14) NDC 0409-4916-14	Hospira, Inc., a Pfizer Company	Not specified	Discontinuation of the manufacture of the drug
Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 76329-3352-1) NDC 76329-3352-1	Amphastar Pharmaceuticals, Inc.	Limited	Available on allocation
Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5011-4) NDC 51754-5011-4	Exela Pharma Sciences, LLC	Available	-
Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 51754-5001-5) NDC 51754-5001-5	Exela Pharma Sciences, LLC	Available	-
Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 63323-089-50) NDC 63323-089-50	Fresenius Kabi USA, LLC	Available	Check wholesalers for inventory
Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 81298-7620-3) NDC 81298-7620-3	Long Grove Pharmaceuticals LLC	Available	-
Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-4900-14) NDC 0409-4900-14	Hospira, Inc., a Pfizer Company	Not specified	Discontinuation of the manufacture of the drug
Sodium Bicarbonate, Injection, 84 mg/1 mL (NDC 0409-6637-14) NDC 0409-6637-14	Hospira, Inc., a Pfizer Company	Not specified	Discontinuation of the manufacture of the drug

Related medications in shortage

Other Endocrinology/Metabolism, Gastroenterology, Pediatric medications currently on the FDA shortage list — useful context if you and your prescriber are weighing alternatives. Always confirm with your pharmacist.

Change log

No changes recorded yet.
Tracking began Oct 1, 2026. We check the FDA every 6 hours; any real change - a manufacturer moving from Limited to Available, a new recovery date, a new listing - shows up here with its date.

Cite this: “FDA drug-shortage status for Sodium Bicarbonate Injection (FDA data as of Nov 7, 2025). Shortage Watch, openFDA.”

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FDA data last synced Oct 1, 2026 (FDA record dated Sep 30, 2026).