When will Methylprednisolone Acetate Injection be back in stock?

The FDA lists an estimated recovery date per manufacturer where known; check the FDA note column below. National FDA records do not reflect your local pharmacy's shelf.

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Methylprednisolone Acetate Injection

Brand names: Depo-Medrol, Methylprednisolone Acetate

Category: Rheumatology

Unavailable 7Limited 7Available 9

FDA status: Current · Last FDA update: Sep 21, 2026 · First posted: Jun 16, 2022 (in shortage 4 years 3 months) · 5 manufacturers, 23 listed presentations

As of Sep 21, 2026, the FDA lists Methylprednisolone Acetate Injection as currently in shortage. Of 23 manufacturer presentations, 7 Unavailable, 7 Limited, 9 Available.

Ask your pharmacist: which of the 5 manufacturers below can they order right now, and whether a different strength or form of Methylprednisolone Acetate Injection is available. For alternatives, talk to your prescriber — see what to do if your medication is in shortage.

Presentation & package NDC	Manufacturer	Availability	FDA note
Depo-medrol, Injection, 20 mg/1 mL (NDC 0009-0274-01) NDC 0009-0274-01	Pfizer Inc.	Available	-
Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 55150-313-01) NDC 55150-313-01	Eugia US LLC	Unavailable	On backorder. Recovery: TBD. Check wholesalers for inventory
Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-23) NDC 0009-3073-23	Pfizer Inc.	Unavailable	Next Delivery: October 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay
Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-22) NDC 0009-3073-22	Pfizer Inc.	Unavailable	Next Delivery: October 2026; Estimated Recovery: December 2026
Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-05) NDC 25021-820-05	Sagent Pharmaceuticals	Unavailable	Estimated recovery: November 2026
Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-10) NDC 25021-820-10	Sagent Pharmaceuticals	Unavailable	Estimated recovery: November 2026,
Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-1) NDC 70121-1573-1	Amneal Pharmaceuticals	Limited	On backorder. Estimated recovery: late July
Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-01) NDC 0009-3073-01	Pfizer Inc.	Limited	Limited Supply Available. Next Delivery: October 2026; Estimated Recovery: December 2026
Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-03) NDC 0009-0280-03	Pfizer Inc.	Limited	Limited Supply Available. Next Delivery: November 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay
Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-03) NDC 0009-3073-03	Pfizer Inc.	Limited	Limited Supply Available. Next Delivery: September 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay
Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-5) NDC 70121-1573-5	Amneal Pharmaceuticals	Available	-
Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-02) NDC 0009-0280-02	Pfizer Inc.	Available	-
Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-51) NDC 0009-0280-51	Pfizer Inc.	Available	-
Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-52) NDC 0009-0280-52	Pfizer Inc.	Available	-
Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 55150-314-01) NDC 55150-314-01	Eugia US LLC	Unavailable	On backorder. Recovery: TBD. Check wholesalers for inventory
Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 42023-240-01) NDC 42023-240-01	Par Health, USA LLC	Unavailable	Estimated recovery: TBD
Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-03) NDC 0009-3475-03	Pfizer Inc.	Limited	Limited Supply Available. Next Delivery: September 2026; Estimated Recovery: March 2027; Shortage per Manufacturer: Manufacturing Delay
Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-01) NDC 0009-3475-01	Pfizer Inc.	Limited	Limited Supply Available. Next Delivery and Estimated Recovery: December 2026
Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 25021-821-05) NDC 25021-821-05	Sagent Pharmaceuticals	Limited	Estimated recovery: November 2026, Product on hand is 8-12 months of dating prior to expiry
Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-1) NDC 70121-1574-1	Amneal Pharmaceuticals	Available	-
Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-5) NDC 70121-1574-5	Amneal Pharmaceuticals	Available	-
Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-02) NDC 0009-0306-02	Pfizer Inc.	Available	-
Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-12) NDC 0009-0306-12	Pfizer Inc.	Available	-

Related medications in shortage

Other Rheumatology medications currently on the FDA shortage list — useful context if you and your prescriber are weighing alternatives. Always confirm with your pharmacist.

Change log

No changes recorded yet.
Tracking began Oct 1, 2026. We check the FDA every 6 hours; any real change - a manufacturer moving from Limited to Available, a new recovery date, a new listing - shows up here with its date.

Cite this: “FDA drug-shortage status for Methylprednisolone Acetate Injection (FDA data as of Sep 21, 2026). Shortage Watch, openFDA.”

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FDA data last synced Oct 1, 2026 (FDA record dated Sep 30, 2026).