{
 "generic_name": "Bupivacaine Hydrochloride Injection",
 "slug": "bupivacaine-hydrochloride-injection",
 "brand_names": [
  "Bupivacaine Hydrochloride",
  "Bupivacaine Spinal",
  "Marcaine",
  "Marcaine Spinal",
  "Sensorcaine",
  "Sensorcaine Mpf"
 ],
 "fda_status": [
  "Current",
  "To Be Discontinued"
 ],
 "last_fda_update": "09/22/2026",
 "first_posted": "02/20/2018",
 "synced_at": "2026-10-01T04:04:04.751Z",
 "presentations": [
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1761-62",
   "presentation": "Marcaine, Injection, 0.75% 15 mg/2 mL (NDC 0409-1761-62)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-464-31",
   "presentation": "Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-31)",
   "availability": "Unavailable",
   "availability_raw": "Unavailable",
   "fda_note": "Estimated recovery: TBD"
  },
  {
   "company": "Aspiro Pharma Limited",
   "package_ndc": "31722-275-32",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-32)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Aspiro Pharma Limited",
   "package_ndc": "31722-275-34",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 31722-275-34)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Eugia US LLC",
   "package_ndc": "55150-249-50",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-249-50)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Eugia US LLC",
   "package_ndc": "55150-167-10",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-167-10)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Eugia US LLC",
   "package_ndc": "55150-168-30",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-168-30)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-465-57",
   "presentation": "Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-465-57)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-464-17",
   "presentation": "Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-17)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-464-37",
   "presentation": "Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-37)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Somerset Therapeutics, LLC",
   "package_ndc": "70069-752-25",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-25)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Somerset Therapeutics, LLC",
   "package_ndc": "70069-752-10",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-10)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Somerset Therapeutics, LLC",
   "package_ndc": "70069-752-01",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 70069-752-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Kindos Pharmaceuticals Co. Ltd.",
   "package_ndc": "71288-723-52",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-723-52)",
   "availability": "Not specified",
   "availability_raw": null,
   "fda_note": "Discontinuation of the manufacture of the drug"
  },
  {
   "company": "Kindos Pharmaceuticals Co. Ltd.",
   "package_ndc": "71288-722-32",
   "presentation": "Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-722-32)",
   "availability": "Not specified",
   "availability_raw": null,
   "fda_note": "Discontinuation of the manufacture of the drug"
  },
  {
   "company": "ONESOURCE SPECIALTY PTE LTD",
   "package_ndc": "72266-263-10",
   "presentation": "Bupivacaine Hydrochloride PRESERVATIVE FREE, Injection, 2.5 mg/1 mL\n5mg / 1mL (NDC 72266-263-10)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Distributed by Fosun Pharma USA Inc."
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-466-31",
   "presentation": "Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-31)",
   "availability": "Unavailable",
   "availability_raw": "Unavailable",
   "fda_note": "Estimated recovery: TBD"
  },
  {
   "company": "Kindos Pharmaceuticals Co. Ltd.",
   "package_ndc": "71288-725-32",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-725-32)",
   "availability": "Limited",
   "availability_raw": "Limited Availability",
   "fda_note": "Meitheal Pharmaceuticals is distributor/labeler"
  },
  {
   "company": "Kindos Pharmaceuticals Co. Ltd.",
   "package_ndc": "71288-726-52",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-726-52)",
   "availability": "Limited",
   "availability_raw": "Limited Availability",
   "fda_note": "Meitheal Pharmaceuticals is distributor/labeler"
  },
  {
   "company": "Aspiro Pharma Limited",
   "package_ndc": "31722-276-32",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 31722-276-32)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Aspiro Pharma Limited",
   "package_ndc": "31722-276-34",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 31722-276-34)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Eugia US LLC",
   "package_ndc": "55150-250-50",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-250-50)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Eugia US LLC",
   "package_ndc": "55150-169-10",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-169-10)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Eugia US LLC",
   "package_ndc": "55150-170-30",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-170-30)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-466-37",
   "presentation": "Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-37)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-467-57",
   "presentation": "Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-467-57)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-466-17",
   "presentation": "Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-17)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Somerset Therapeutics, LLC",
   "package_ndc": "70069-753-25",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-25)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Somerset Therapeutics, LLC",
   "package_ndc": "70069-753-10",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-10)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Somerset Therapeutics, LLC",
   "package_ndc": "70069-753-01",
   "presentation": "Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 70069-753-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Huons Co., Ltd",
   "package_ndc": "73293-0002-2",
   "presentation": "Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 73293-0002-2)",
   "availability": "Unavailable",
   "availability_raw": "Unavailable",
   "fda_note": "Estimated recovery: TBD"
  },
  {
   "company": "Kindos Pharmaceuticals Co. Ltd.",
   "package_ndc": "71288-728-32",
   "presentation": "Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 71288-728-32)",
   "availability": "Limited",
   "availability_raw": "Limited Availability",
   "fda_note": "Meitheal Pharmaceuticals is distributor/labeler"
  },
  {
   "company": "Aspiro Pharma Limited",
   "package_ndc": "31722-277-32",
   "presentation": "Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 31722-277-32)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Aspiro Pharma Limited",
   "package_ndc": "31722-277-34",
   "presentation": "Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 31722-277-34)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Eugia US LLC",
   "package_ndc": "55150-171-10",
   "presentation": "Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 55150-171-10)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Eugia US LLC",
   "package_ndc": "55150-172-30",
   "presentation": "Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 55150-172-30)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-472-37",
   "presentation": "Sensorcaine, Injection, 7.5 mg/1 mL (NDC 63323-472-37)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Fresenius Kabi USA, LLC",
   "package_ndc": "63323-472-17",
   "presentation": "Sensorcaine, Injection, 7.5 mg/1 mL (NDC 63323-472-17)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Check wholesalers for inventory"
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-2253-25",
   "presentation": "Marcaine, Injection, 225 mg/30 mL (NDC 0409-2253-25)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Historical NDC: 0409-1582-29"
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-0525-25",
   "presentation": "Marcaine, Injection, 250 mg/50 mL (NDC 0409-0525-25)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Historical NDC: 0409-1610-50"
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1160-01",
   "presentation": "Bupivacaine Hydrochloride, Injection, 125 mg/50 mL (2.5 mg/mL) (NDC 0409-1160-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1162-02",
   "presentation": "Bupivacaine Hydrochloride, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-1162-02)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1165-02",
   "presentation": "Bupivacaine Hydrochloride, Injection, 225 mg/30 mL (7.5 mg/mL) (NDC 0409-1165-02)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1159-01",
   "presentation": "Bupivacaine Hydrochloride, Injection, 25 mg/10 mL (2.5 mg/mL) (NDC 0409-1159-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1163-01",
   "presentation": "Bupivacaine Hydrochloride, Injection, 250 mg/50 mL (5 mg/mL) (NDC 0409-1163-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1162-01",
   "presentation": "Bupivacaine Hydrochloride, Injection, 50 mg/10 mL (5 mg/mL) (NDC 0409-1162-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1159-02",
   "presentation": "Bupivacaine Hydrochloride, Injection, 75 mg/30 mL (2.5 mg/mL) (NDC 0409-1159-02)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-3613-01",
   "presentation": "Bupivacaine Hydrochloride, Injection, Bupivacaine Spinal 15 mg/2 mL (7.5 mg/mL in 8.25% dextrose) (NDC 0409-3613-01)",
   "availability": "Limited",
   "availability_raw": "Limited Availability",
   "fda_note": "Limited Supply Available. Next Delivery: May 2027; Estimated Recovery: June 2027"
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1761-10",
   "presentation": "Marcaine, Injection, 0.75% 15 mg/2 mL (7.5 mg/mL) in Dextrose 8.25% (NDC 0409-1761-10)",
   "availability": "Unavailable",
   "availability_raw": "Unavailable",
   "fda_note": "Next Delivery: November 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay"
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1530-01",
   "presentation": "Marcaine, Injection, 150 mg/30 mL (5 mg/mL) (NDC 0409-1530-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-2510-01",
   "presentation": "Marcaine, Injection, 25 mg/10 mL (2.5 mg/mL) (NDC 0409-2510-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-5010-01",
   "presentation": "Marcaine, Injection, 50 mg/10 mL (5 mg/mL) (NDC 0409-5010-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-7535-01",
   "presentation": "Marcaine, Injection, 75 mg/30 mL (2.5 mg/mL) (NDC 0409-7535-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-2253-01",
   "presentation": "Marcaine, Injection, Marcaine 225 mg/30 mL (7.5 mg/mL) (NDC 0409-2253-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": "Historical NDC: 0409-1582-29"
  },
  {
   "company": "Hospira, Inc., a Pfizer Company",
   "package_ndc": "0409-1165-01",
   "presentation": "Marcaine, Injection, Marcaine 75 mg/10 mL (7.5 mg/mL) (NDC 0409-1165-01)",
   "availability": "Available",
   "availability_raw": "Available",
   "fda_note": null
  }
 ],
 "changes": []
}